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Tuesday, August 4, 2020 | History

2 edition of Respiratory action of lobeline in the dog found in the catalog.

Respiratory action of lobeline in the dog

Samson Wright

Respiratory action of lobeline in the dog

by Samson Wright

  • 392 Want to read
  • 35 Currently reading

Published by Lancet in [London] .
Written in English

    Subjects:
  • Respiratory system.

  • Edition Notes

    Caption title.

    Statementby Samson Wright and F. R. Curtis.
    ContributionsCurtis, F. R.
    The Physical Object
    Pagination4p. ;
    ID Numbers
    Open LibraryOL21799510M

      Lobelia is an herb native to North America, where it has been used for centuries by Native Americans for coughing and chest pains, as well as for inducing , lobelia is still used in herbal remedies; however, most people are unaware of its health benefits.   The ribs are lightweight and resilient, consisting of three types: true, false and floating form most of the thoracic cage, extending from the posterior to the anterior thoracic walls. They are attached at their anterior ends by costal cartilages, which either provide direct attachment to the sternum, or the costal margin.A few ribs, the so-called floating ribs, .

    Lobelia, also called Indian tobacco, has a long history of use in connection with respiratory ailments, such as asthma, bronchitis, pneumonia, and coughs. Lobeline, an active constituent in the lobelia plant, is very similar to nicotine in its effect on the central nervous system. Therefore, it is concluded that there is no humoral agent produced in the arterial blood of a dog subjected to this type of exercise. The normalcy of the respiratory apparatus in the humoral dog after the establishment of the cross circulation was tested by CO 2 inhalation and lobeline administration and it was found to be adequate.

    Overview. Lobelia (Lobelia inflata), also called Indian tobacco, has a long history of use as an herbal remedy for respiratory conditions such as asthma, bronchitis, pneumonia, and ically, Native Americans smoked lobelia as a treatment for asthma. In the 19th century, American physicians prescribed lobelia to induce vomiting in order remove toxins .   Lobelia is considered LIKELY UNSAFE for most people when taken by mouth. Side effects include nausea, vomiting, diarrhea, cough, dizziness, tremors, and more serious effects.. Overdose may cause many serious toxic effects including sweating, convulsions, fast heartbeat, very low blood pressure, collapse, coma, and possibly gram of .


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Respiratory action of lobeline in the dog by Samson Wright Download PDF EPUB FB2

RESPIRATORY ACTION OF LOBELINE IN THE DOG. Previous Article A CASE OF DISLOCATION OF THE RIGHT INNOMINATE BONE, ASSOCIATED WITH LACERATION OF THE RIGHT KIDNEY. Next Article A CASE OF AGRANULOCYTIC ANGINA. Article Info Publication History.

Published: 02 March by: 3. Lobelia (Lobelia inflata) is a plant used in herbal and homeopathic to expel mucus from the respiratory tract, it is used to treat respiratory problems. In addition, some individuals use lobelia to help them quit smoking, sooth muscles, support alcoholism recovery, and this wide range of uses is attractive, lobelia is listed in the U.S.

Food and Drug. However, abolition of apncea did not reveal any respiratory stimulant action. Bemegride 10 mg/kg given to anaesthetized vagotomized dogs, on the other hand caused a marked temporary increase in respiratory rate (fig.

lb). Ethamivan still produced hypotension in the vagotomized dog, but this was not accompanied by : J.R. Campbell, D.D.

Lawson, J. Sanford. The Lancet Observations ON THE ACTION OF LOBELINE. F.R. CurtisM.B., B.S. LEEDS Samson Wright Respiratory action of lobeline in the dog book, M.R.C.P. LOND.

(From the Physiological Laboratory, Middlesex Hospital Medical School.), United Kingdom INTEREST in the action of the lobelia alkaloids was stimulated when Wieland1 first isolated in a pure crystalline compound from Lobelia inflata (Indian Cited by: 8.

DALY M de B, SCHWEITZER A. Reflex bronchomotor responses to stimulation of receptors in the regions of the carotid sinus and arch of the aorta in the dog and cat.

J Physiol. May; (4)– [PMC free article] ECKENHOFF JE, COMROE JH., Jr Blocking of tetraethylammonium on lobelin-induced thoracic by: 7. Lobelia inflata (Indian tobacco) contains lobeline and other pyridine alkaloids.

It has been used as an emetic, antidepressant, respiratory stimulant, an aid to smoking cessation, and a treatment for metamfetamine abuse [2]. Lobeline has peripheral effects similar to those of nicotine, whereas its central activity may be different.

Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during h smokeless tobacco deprivation. Nicotine Tob Res ; View abstract. Abstract. The effect has been studied of sodium cromoglycate (SCG) on the activity of 'C' fibre sensory nerve endings in the canine lung.

Pretreatment with SCG ( microgram/kg i.v.) reduced the excitation of these endings by capsaicin (10 microgram/kg i.v.) for approximately 45 min. Read the latest articles of The Lancet atElsevier’s leading platform of peer-reviewed scholarly literature. BEVAN JA. Action of lobeline and capsaicine on afferent endings in the pulmonary artery of the cat.

Circ Res. May; – [COLERIDGE JC, KIDD C. Electrophysiological evidence of baroreceptors in the pulmonary artery of the dog. Lobelia is a genus of flowering plants that includes approximately species and was popular in traditional Native American medicine as an emetic, expectorant and respiratory a is currently used as an adjunctive for the treatment of asthma and other respiratory disorders.

The active constituent of Lobelia is the alkaloid lobeline, which is. This Journal. Back; Journal Home; Online First; Current Issue; All Issues; Special Issues; About the journal; Journals.

Back; The Lancet; The Lancet Child. Lobeline is a pyridine alkaloid found in a variety of plants, particularly those in the genus Lobelia, including Indian tobacco (Lobelia inflata), Devil's tobacco (Lobelia tupa), cardinal flower (Lobelia cardinalis), great lobelia (Lobelia siphilitica), Lobelia chinensis, and Hippobroma its pure form, it is a white amorphous powder which is freely soluble in water.

1. Introduction. In two recent studies carried out on patients with cardiovascular disease, respiratory sensations felt with moderate exercise were demonstrated to be similar to those evoked by small doses of intravenously injected lobeline, an alkaloid (Dehghani et al.,Anand et al., ).These respiratory sensations were, a shortness of breath, pressure.

In contrast to control subjects, the early respiratory events and the noxious sensations evoked by injections of lobeline (18–60 μg kg −1) did not occur in subjects with recent bilateral lung suggests that the early respiratory sensations are mediated by the discharge of receptors in the lungs.

Respiratory System of the Dog The pictures in this section are reprinted with permission by the copyright owner, Hill's Pet Nutrition, from the Atlas of Veterinary Clinical Anatomy. These illustrations should not be downloaded, printed or copied except for.

In Meyler's Side Effects of Drugs (Sixteenth Edition), Lobelia inflata. Lobelia inflata (Indian tobacco) contains lobeline and other pyridine alkaloids. It has been used as an emetic, antidepressant, respiratory stimulant, an aid to smoking cessation, and a treatment for metamfetamine abuse [2].Lobeline has peripheral effects similar to those of nicotine, whereas.

Lobelia poisoning occurs when your dog consumes parts of the lobelia plant and is exposed to lobeline, the plant’s toxic principle. In terms of its toxicity level, lobelia is rated a major toxin.

This means that ingestion of the plant can be the. Coleridge HM, Coleridge JCG (a) Afferent vagal C-fibers in the dog lung: their discharge during spontaneous breathing, and their stimulation by alloxan and pulmonary congestion.

In: Paintal AS, Gill-Kumar P (eds) Respiratory adaption, capillary exchange and reflex mechanisms. Vallabhbhai Patel Chest Inst, Delhi, p – Google Scholar. Lobeline hydrochloride was used as an emergency respiratory stimulant in intravenous, intramuscular, and subcutaneous doses by conventional physicians in the U.S.

beginning in (Osol and Farrar). This use was still listed in pharmacology texts as. BANISTER J, FEGLER G, HEBB C. Initial respiratory responses to the intratracheal inhalation of phosgene or ammonia. Q J Exp Physiol Cogn Med Sci.

Nov; 35 (3)–pl. BEVAN JA, KINNISON GL. ACTION OF LOBELINE ON PULMONARY ARTERY MECHANORECEPTORS OF THE CAT. Circ Res. Jul; –In lobeline poisoning the primary cause of death is respiratory paralysis. In cases where a large amount has been ingested, it is highly likely that artificial respiration will be needed to keep the patient breathing and alive until antidotes and the body's natural detoxification mechanisms can destroy the toxin and reduce it to non-toxic.

The lungs are richly endowed with unmyelinated vagal afferents which terminate in receptors known either as juxtapulmonary capillary receptors (J receptors; Paintal, ) or pulmonary C fibres (Coleridge & Coleridge, ).It is believed that the cardiovascular and respiratory changes which follow shortly after injection of lobeline in human subjects and .